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Introduction In the last two decades, the worldwide spreading of overweight and obesity has resulted in an increase in the prevalence of nonalcoholic fatty liver disease (NAFLD) which is now becoming the most common liver disease. By now
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Introduction With the growing prevalence of obesity and diabetes worldwide, liver diseases are becoming more frequent. Nonalcoholic fatty liver disease (NAFLD) is now the one of the most common forms of liver disease found across the globe
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Introduction Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease characterised by hepatic steatosis that affects approximately 25% of the general population ( Younossi et al. 2016 , Loomba et al. 2021 ). NAFLD includes a
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-Tocopherol and fatty liver disease Although fatty liver disease (NAFLD, now termed metabolic dysfunction-associated steatotic liver disease (MASLD) ( Rinella et al. 2023 )) has not been reported frequently in persons with AVED, there is a case report of
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and lifestyle-related diseases has been found ( Rayman & Stranges 2013 , Rees et al. 2013 , Vinceti et al. 2022 ). In type 2 diabetes patients, levels of SELENOP mRNA in the liver and blood SELENOP protein were increased ( Misu et al. 2010 ). A
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. 2013 , Yimlamai et al. 2014 , Pepe-Mooney et al. 2019 ). It is worth to note that HPC-dependent hepatic regeneration is not effective in repairing the loss of liver mass in severe or chronic liver diseases ( Weng et al. 2015 ). Furthermore, the
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to counteract sepsis ( Beltrán-García et al. 2022 ), in the dysfunction of endothelial nitric oxide synthase occurring in vascular diseases ( Negre-Salvayre et al. 2022 ), in liver regeneration ( Bellanti et al. 2022 ), in the complex
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diseases. If left untreated, it can lead to acquired immune deficiency syndrome (AIDS) which is characterized, as its name indicates, by a deficiency of the immune system, which predisposes the patients to the development of certain cancers, infections, or
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to cholesterol homeostasis since it regulates one of the two pathways of bile acid synthesis ( Javitt 1994 ), and more recently it has been demonstrated to be a good ligand of quite a number of receptors, like liver X receptors ( Janowski et al
PULSALYS SATT Lyon-Saint Etienne, Villeurbanne, France
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-inflammatory molecule has been proposed as treatment for several pharmaceutical applications, such as neurodegenerative diseases, cancer, IBD and ethanol-induced oxidative injuries in brain, liver, heart and kidney ( Barzegar & Moosavi-Movahedi 2011 , Jakubczyk et al
