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Ebenezer Tunde Olayinka Biochemistry unit, Department of Chemical Sciences, Ajayi Crowther University, Oyo, Nigeria

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Toluwalase Oreofe Oni Biochemistry unit, Department of Chemical Sciences, Ajayi Crowther University, Oyo, Nigeria

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Abosede Temitope Olajide Biochemistry unit, Department of Chemical Sciences, Ajayi Crowther University, Oyo, Nigeria

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Babajide Oluwaseun Ajayi Biochemistry unit, Department of Chemical Sciences, Ajayi Crowther University, Oyo, Nigeria

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Samuel Abiodun Kehinde Biochemistry unit, Department of Chemical Sciences, Ajayi Crowther University, Oyo, Nigeria
Department of Environmental Health Science, Ajayi Crowther University, Oyo, Nigeria

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. Assay of inflammation biomarkers Nitric oxide concentration was determined by estimating nitrite level following the method of Green et al. (1982) . Nitrite measurement is used to quantify nitric oxide (NO), one of its stable oxidation products. A

Article Type:
Research Article
DOI:
https://doi.org/10.1530/REM-22-0018
Volume/Issue:
Volume 2022: Issue 1
Open access
Noemi Iaia Department of Clinical and Biological Sciences, University of Turin, San Luigi Hospital, Orbassano (Turin), Italy

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Federico Canzoneri Soremartec Italia Srl, Ferrero Group, Alba, Italy

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Ginevra Rosso Soremartec Italia Srl, Ferrero Group, Alba, Italy

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Roberto Menta Soremartec Italia Srl, Ferrero Group, Alba, Italy

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Fiorella Biasi Department of Clinical and Biological Sciences, University of Turin, San Luigi Hospital, Orbassano (Turin), Italy

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2015 The role of p38 MAPK in the induction of intestinal inflammation by dietary oxysterols: modulation by wine phenolics . Food and Function 6 1218 – 1228 . ( https://doi.org/10.1039/c4fo01116c ) Hur SJ Park GB Joo ST 2007 Formation of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/REM-22-0022
Volume/Issue:
Volume 2023: Issue 1
Open access
Imen Ghzaiel Team ‘Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism’ EA7270/Inserm, University Bourgogne Franche-Comté, Dijon, France
Lab-NAFS ‘Nutrition-Functional Food & Vascular Health’, Faculty of Medicine, University of Monastir, Monastir, Tunisia
Faculty of Sciences of Tunis, University Tunis-El Manar, Tunis, Tunisia

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Khouloud Sassi Team ‘Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism’ EA7270/Inserm, University Bourgogne Franche-Comté, Dijon, France

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Amira Zarrouk Lab-NAFS ‘Nutrition-Functional Food & Vascular Health’, Faculty of Medicine, University of Monastir, Monastir, Tunisia
Faculty of Medicine, University of Sousse, Sousse, Tunisia

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Shubhrima Ghosh School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, The University of Dublin, College Green, Dublin 2, Ireland

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Irundika H K Dias Aston Medical School, Aston University, Birmingham, UK

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Thomas Nury Team ‘Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism’ EA7270/Inserm, University Bourgogne Franche-Comté, Dijon, France

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Mohamed Ksila Team ‘Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism’ EA7270/Inserm, University Bourgogne Franche-Comté, Dijon, France
Department of Biology, Faculty of Sciences, University Tunis-El Manar, Loboratory of Neurophysiology, Cellular Physiopathology and Valorisation of BioMolecules, LR18ES03, Tunis, Tunisia

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Soukaina Essadek Team ‘Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism’ EA7270/Inserm, University Bourgogne Franche-Comté, Dijon, France
Laboratory of Biochemistry, Neurosciences, Natural Resources and Environment, Faculty of Sciences & Techniques, University Hassan I, Settat, Morocco

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Mounia Tahri Joutey Team ‘Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism’ EA7270/Inserm, University Bourgogne Franche-Comté, Dijon, France
Laboratory of Biochemistry, Neurosciences, Natural Resources and Environment, Faculty of Sciences & Techniques, University Hassan I, Settat, Morocco

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Fatiha Brahmi Laboratory Biomathématique, Biochimie, Biophysique et Scientométrie, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia, Algeria

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Wafa Mihoubi Laboratoire de Biotechnologie Moléculaire des Eucaryotes, Centre de Biotechnologie de Sfax, Université de Sfax, Sfax, Tunisia

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Sandrine Rup-Jacques LCPMC-A2, ICPM, Department of Chemistry, University Lorraine, Metz Technopôle, Metz, France

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Mohammad Samadi LCPMC-A2, ICPM, Department of Chemistry, University Lorraine, Metz Technopôle, Metz, France

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Leila Rezig University of Carthage, National Institute of Applied Sciences and Technology, LR11ES26, LIP-MB ‘Laboratory of Protein Engineering and Bioactive Molecules’, Tunis, Tunisia
University of Carthage, High Institute of Food Industries, El Khadra City, Tunis, Tunisia

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Smail Meziane Institut Européen des Antioxydants, Neuves-Maisons, France

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Taoufik Ghrairi Department of Biology, Faculty of Sciences, University Tunis-El Manar, Loboratory of Neurophysiology, Cellular Physiopathology and Valorisation of BioMolecules, LR18ES03, Tunis, Tunisia

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Olfa Masmoudi-Kouki Department of Biology, Faculty of Sciences, University Tunis-El Manar, Loboratory of Neurophysiology, Cellular Physiopathology and Valorisation of BioMolecules, LR18ES03, Tunis, Tunisia

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Sonia Hammami Lab-NAFS ‘Nutrition-Functional Food & Vascular Health’, Faculty of Medicine, University of Monastir, Monastir, Tunisia

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Boubker Nasser Laboratory of Biochemistry, Neurosciences, Natural Resources and Environment, Faculty of Sciences & Techniques, University Hassan I, Settat, Morocco

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Mohamed Hammami Lab-NAFS ‘Nutrition-Functional Food & Vascular Health’, Faculty of Medicine, University of Monastir, Monastir, Tunisia

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Yuqin Wang Swansea University Medical School, Swansea, Wales, UK

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William J Griffiths Swansea University Medical School, Swansea, Wales, UK

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Anne Vejux Team ‘Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism’ EA7270/Inserm, University Bourgogne Franche-Comté, Dijon, France

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Gérard Lizard Team ‘Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism’ EA7270/Inserm, University Bourgogne Franche-Comté, Dijon, France

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cytokinic and non-cytokinic inflammation, often leading to an apoptotic mode of cell death associated with autophagy criteria. The type of cell death frequently induced by 7KC, as well as by other cytotoxic oxysterols (7β-hydroxycholesterol, 24S

Article Type:
Review Article
DOI:
https://doi.org/10.1530/REM-22-0005
Volume/Issue:
Volume 2022: Issue 1
Open access
Tania Medali Biological Adaptation and Ageing (B2A), CNRS UMR-8256/INSERM ERL U-1164, Biological Institute Paris-Seine, Sorbonne University, Paris, France

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Dominique Couchie Biological Adaptation and Ageing (B2A), CNRS UMR-8256/INSERM ERL U-1164, Biological Institute Paris-Seine, Sorbonne University, Paris, France

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Nathalie Mougenot Plateforme PECMV, UMS28 INSERM, Faculté de Médecine, Sorbonne University, Paris, France

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Maria Mihoc Plateforme PECMV, UMS28 INSERM, Faculté de Médecine, Sorbonne University, Paris, France

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Olaf Bergmann Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden CRTD, TU Dresden, Dresden, Germany

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Wouter Derks Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden CRTD, TU Dresden, Dresden, Germany

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Celio X Santos BHF Centre of Excellence King's College London, The James Black Centre, London, UK

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Bertrand Friguet Biological Adaptation and Ageing (B2A), CNRS UMR-8256/INSERM ERL U-1164, Biological Institute Paris-Seine, Sorbonne University, Paris, France

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Mustapha Rouis Biological Adaptation and Ageing (B2A), CNRS UMR-8256/INSERM ERL U-1164, Biological Institute Paris-Seine, Sorbonne University, Paris, France

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inflammation of the arterial wall. The inflammatory process plays a key role in all stages of atherosclerosis ( Libby 2002 ). Several studies demonstrated the role of activated macrophages and activated T lymphocytes in atheroma plaque destabilization ( Libby

Article Type:
Research Article
DOI:
https://doi.org/10.1530/REM-23-0029
Volume/Issue:
Volume 2024: Issue 1
Open access
Salvatore Sutti Department of Health Sciences and Interdisciplinary Research Centre for Autoimmune Diseases, University of East Piedmont, Novara, Italy

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Emanuele Albano Department of Health Sciences and Interdisciplinary Research Centre for Autoimmune Diseases, University of East Piedmont, Novara, Italy

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(NASH), in which liver steatosis combines with parenchymal damage (hepatocyte apoptosis and ballooning, focal necrosis), lobular/portal inflammation, and variable degree of fibrosis ( Powell et al. 2021 ). Liver fibrosis in NASH often progresses to

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Review Article
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Alteration of redox homeostasis and liver diseases
DOI:
https://doi.org/10.1530/REM-22-0002
Volume/Issue:
Volume 2022: Issue 1
Open access
Valeria Cordone Department of Environment and Prevention, University of Ferrara, Ferrara, Italy

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Alessandra Pecorelli Animal Science Department, Plants for Human Health Institute, North Carolina State University, Kannapolis Research Campus, Kannapolis, North Carolina, USA

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Giuseppe Valacchi Department of Environment and Prevention, University of Ferrara, Ferrara, Italy
Animal Science Department, Plants for Human Health Institute, North Carolina State University, Kannapolis Research Campus, Kannapolis, North Carolina, USA
Department of Food and Nutrition, Kyung Hee University, Seoul, South Korea

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energetic condition ( Imai et al. 2000 ). Not only this, SIRTs play critical roles in the regulation of cellular homeostasis, in particular oxidative stress, inflammation, metabolism and senescence ( Vachharajani et al. 2016 , Singh et al. 2018 , Lee

Article Type:
Review Article
DOI:
https://doi.org/10.1530/REM-22-0004
Volume/Issue:
Volume 2022: Issue 1
Open access
Mathieu Repellin LAGEPP UMR 5007, Univ Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France
PULSALYS SATT Lyon-Saint Etienne, Villeurbanne, France

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Hanäé Guerin LAGEPP UMR 5007, Univ Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France

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Giuseppina Catania LAGEPP UMR 5007, Univ Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France

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Giovanna Lollo LAGEPP UMR 5007, Univ Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France

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and external supplementation issue from common diet. However, in pathological conditions related to ROS overproduction, antioxidant defense is overwhelmed by sustained inflammation resulting in a disturbed redox balance ( Poljsak et al. 2013

Article Type:
Review Article
DOI:
https://doi.org/10.1530/REM-23-0021
Volume/Issue:
Volume 2023: Issue 1
Open access
Heaji Lee Department of Food and Nutrition, Kyung Hee University, Dongdaemun-gu, Seoul, Republic of Korea

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Soo Jin Yang Department of Food and Nutrition, Seoul Women’s University, Seoul, Korea

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Yunsook Lim Department of Food and Nutrition, Kyung Hee University, Dongdaemun-gu, Seoul, Republic of Korea

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, and inflammation in diabetic pathology. Loss of muscle mass and strength can be controlled by various lifestyle factors, mainly exercise training and diet. The role of exercise in sarcopenia has been extensively investigated. Moreover, diverse

Article Type:
Review Article
DOI:
https://doi.org/10.1530/REM-22-0001
Volume/Issue:
Volume 2022: Issue 1
Open access
Kota Saito Department of Molecular Pathobiology, Faculty of Pharmaceutical Sciences, Kyushu University, Maidashi Higashi-ku, Fukuoka, Japan

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Yuta Matsuoka Center for Cancer Immunotherapy and Immunobiology, Graduate School of Medicine, Kyoto University, Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Japan

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Masami Abe Department of Molecular Pathobiology, Faculty of Pharmaceutical Sciences, Kyushu University, Maidashi Higashi-ku, Fukuoka, Japan

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Nao Kato Department of Molecular Pathobiology, Faculty of Pharmaceutical Sciences, Kyushu University, Maidashi Higashi-ku, Fukuoka, Japan

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Kazushi Morimoto Department of Molecular Pathobiology, Faculty of Pharmaceutical Sciences, Kyushu University, Maidashi Higashi-ku, Fukuoka, Japan

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Ken-ichi Yamada Department of Molecular Pathobiology, Faculty of Pharmaceutical Sciences, Kyushu University, Maidashi Higashi-ku, Fukuoka, Japan

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wide range of pathological conditions, from relatively mild hepatic steatosis (NAFL) to a more aggressive disease state (nonalcoholic steatohepatitis, NASH) with progressive hepatocellular death and enhanced inflammation ( Singh et al. 2015 ). NASH is

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Alteration of redox homeostasis and liver diseases
DOI:
https://doi.org/10.1530/REM-22-0024
Volume/Issue:
Volume 2023: Issue 1
Open access
Cristina Mas-Bargues Freshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable-Instituto de Salud Carlos III (CIBERFES-ISCIII), INCLIVA, Valencia, Spain

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Consuelo Borrás Freshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable-Instituto de Salud Carlos III (CIBERFES-ISCIII), INCLIVA, Valencia, Spain

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José Viña Freshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable-Instituto de Salud Carlos III (CIBERFES-ISCIII), INCLIVA, Valencia, Spain

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NAC (GlyNAC) on several parameters including GSH concentrations, mitochondrial function, autophagy, oxidative stress, and inflammation. They concluded that GlyNAC treatment improved all these parameters related to premature aging ( Kumar et al. 2020

Article Type:
Review Article
DOI:
https://doi.org/10.1530/REM-22-0017
Volume/Issue:
Volume 2022: Issue 1
Open access