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Giulia Elda Valenti Department of Experimental Medicine, University of Genova, Italy

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Bruno Tasso Department of Pharmacy, University of Genova, Italy

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Nicola Traverso Department of Experimental Medicine, University of Genova, Italy

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Cinzia Domenicotti Department of Experimental Medicine, University of Genova, Italy

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Barbara Marengo Department of Experimental Medicine, University of Genova, Italy

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onset of chemoresistance due to the increase of antioxidant defense ( Kim et al. 2019 , Domenicotti & Marengo 2022 ). Then, the antioxidant response in cancer is triggered by the increased production of reactive oxygen species (ROS) as a result of

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Mariapaola Nitti Department of Experimental Medicine, University of Genoa, Italy

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Jasmin Ortolan Department of Experimental Medicine, University of Genoa, Italy

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Anna Lisa Furfaro Department of Experimental Medicine, University of Genoa, Italy

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& Nitti M 2016b The Nrf2/HO-1 axis in cancer cell growth and chemoresistance . Oxidative Medicine and Cellular Longevity 2016 1958174. ( https://doi.org/10.1155/2016/1958174 ) Furfaro AL Ottonello S Loi G Cossu I Piras S Spagnolo F

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Biplab Kumar Dash Systems Life Sciences Laboratory, Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, Tatara, Kyotanabe, Kyoto, Japan

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Yasuomi Urano Systems Life Sciences Laboratory, Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, Tatara, Kyotanabe, Kyoto, Japan

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Yoshiro Saito Laboratory of Molecular Biology and Metabolism, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan

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Noriko Noguchi Systems Life Sciences Laboratory, Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, Tatara, Kyotanabe, Kyoto, Japan

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://doi.org/10.1093/hmg/ddq113 ) Chen Y Kang M Lu W Guo Q Zhang B Xie Q Wu Y 2012 DJ-1, a novel biomarker and a selected target gene for overcoming chemoresistance in pancreatic cancer . Journal of Cancer Research and Clinical Oncology 138 1463

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