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"redox balance" x

Alteration of redox homeostasis and liver diseases x

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Redox experimental medicine and liver regeneration

Francesco Bellanti

Francesco Bellanti Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy

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Gianluigi Vendemiale

Gianluigi Vendemiale Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy

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Gaetano Serviddio

Gaetano Serviddio Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy

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a regenerative niche (lower panel). Damages inducing liver regeneration often induce alterations in redox balance, which may exert an impact on the regenerative process after injury ( Kamata et al. 2005 , Schwabe & Brenner 2006

Article Type:: Review Article

Collections:: Alteration of redox homeostasis and liver diseases

DOI:: https://doi.org/10.1530/REM-22-0008

Volume/Issue:: Volume 2022: Issue 1

Open access

Role of oxidative stress, gut microbiota and derived metabolites in the etiology and progression of nonalcoholic fatty liver disease

Ankita Das

Ankita Das School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhimpur-Padanpur, Jatni, Khurda, Odisha, India
Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, India

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Arka Jyoti De

Arka Jyoti De School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhimpur-Padanpur, Jatni, Khurda, Odisha, India
Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, India

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Tanuja Mohanty

Tanuja Mohanty School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhimpur-Padanpur, Jatni, Khurda, Odisha, India
Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, India

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Palok Aich

Palok Aich School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhimpur-Padanpur, Jatni, Khurda, Odisha, India
Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, India

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the ER, which causes the formation of ROS and alters the redox balance of the ER. Furthermore, by its direct interaction with PDI, the ER-specific isoform of the NADPH oxidase 4 protein (Nox4) is directly connected to ROS production. Therefore