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Iván Millán Neonatal Research Group, Instituto de Investigación Sanitaria La Fe (IISLAFE), Valencia, Spain
Laboratory of Comparative Neurobiology, Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia, Valencia, Spain
INSERM UMR1141, Université Paris Diderot, Sorbonne Paris Cité, Paris, France

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Marisol Corral-Debrisky INSERM UMR1141, Université Paris Diderot, Sorbonne Paris Cité, Paris, France

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Máximo Vento Neonatal Research Group, Instituto de Investigación Sanitaria La Fe (IISLAFE), Valencia, Spain
Division of Neonatology, University and Polytechnic Hospital La Fe, Valencia, Spain

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Isabel Torres-Cuevas Neonatal Research Group, Instituto de Investigación Sanitaria La Fe (IISLAFE), Valencia, Spain
Department of Physiology, University of Valencia, Burjassot, Spain

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used in models of neurodegenerative diseases, such as Parkinson’s disease and Alzheimer’s disease ( Stetler et al. 2014 ). This review aims to broaden the understanding of the neuroprotective role of HP against oxidative stress. Both terms

Article Type:
Review Article
DOI:
https://doi.org/10.1530/REM-22-0011
Volume/Issue:
Volume 2022: Issue 1
Open access
Jesús Beltrán-García Center for Biomedical Research Network on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Valencia, Spain
Biomedical Research Institute INCLIVA, Valencia, Spain
Department of Physiology, Medicine and Dentistry School, University of Valencia, Valencia, Spain

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Rebeca Osca-Verdegal Center for Biomedical Research Network on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Valencia, Spain
Biomedical Research Institute INCLIVA, Valencia, Spain
Department of Physiology, Medicine and Dentistry School, University of Valencia, Valencia, Spain

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José Luis García-Giménez Center for Biomedical Research Network on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Valencia, Spain
Biomedical Research Institute INCLIVA, Valencia, Spain
Department of Physiology, Medicine and Dentistry School, University of Valencia, Valencia, Spain

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Federico V. Pallardó Center for Biomedical Research Network on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Valencia, Spain
Biomedical Research Institute INCLIVA, Valencia, Spain
Department of Physiology, Medicine and Dentistry School, University of Valencia, Valencia, Spain

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infections ( Man et al. 2017 ). Pyroptosis is triggered by various stimuli, such as changes in membrane potential, oxidative stress, hyperglycemia and even inflammation itself ( Lamkanfi & Dixit 2011 ) ( Fig. 1 ). Among them, oxidative stress has been

Article Type:
Review Article
DOI:
https://doi.org/10.1530/REM-22-0006
Volume/Issue:
Volume 2022: Issue 1
Open access
Ankita Das School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhimpur-Padanpur, Jatni, Khurda, Odisha, India
Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, India

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Arka Jyoti De School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhimpur-Padanpur, Jatni, Khurda, Odisha, India
Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, India

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Tanuja Mohanty School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhimpur-Padanpur, Jatni, Khurda, Odisha, India
Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, India

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Palok Aich School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhimpur-Padanpur, Jatni, Khurda, Odisha, India
Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, India

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hepatocytes. The second stage of this process involves cellular and molecular alterations brought on by oxidative stress and the oxidation of fatty acids in the liver, and the production of reactive oxygen species (ROS) as a result of numerous factors

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Review Article
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Alteration of redox homeostasis and liver diseases
DOI:
https://doi.org/10.1530/REM-23-0016
Volume/Issue:
Volume 2023: Issue 1
Open access
Ebenezer Tunde Olayinka Biochemistry unit, Department of Chemical Sciences, Ajayi Crowther University, Oyo, Nigeria

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Toluwalase Oreofe Oni Biochemistry unit, Department of Chemical Sciences, Ajayi Crowther University, Oyo, Nigeria

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Abosede Temitope Olajide Biochemistry unit, Department of Chemical Sciences, Ajayi Crowther University, Oyo, Nigeria

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Babajide Oluwaseun Ajayi Biochemistry unit, Department of Chemical Sciences, Ajayi Crowther University, Oyo, Nigeria

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Samuel Abiodun Kehinde Biochemistry unit, Department of Chemical Sciences, Ajayi Crowther University, Oyo, Nigeria
Department of Environmental Health Science, Ajayi Crowther University, Oyo, Nigeria

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. Excessive production of hypochlorous acid causes oxidative stress leading to tissue injury ( Ndrepepa 2019 ). TNF-α a proinflammatory cytokine is produced by macrophages during acute inflammation. NO has been demonstrated to be a proinflammatory substance

Article Type:
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DOI:
https://doi.org/10.1530/REM-22-0018
Volume/Issue:
Volume 2022: Issue 1
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Anne Negre-Salvayre Inserm U-1297 – University of Toulouse, Toulouse, France

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Audrey Swiader Inserm U-1297 – University of Toulouse, Toulouse, France

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Paul Guerby Infinity – CNRS INSERM U1291 and Gynecology/Obstetrics Department, Hospital of Toulouse, Toulouse, France

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Robert Salvayre Inserm U-1297 – University of Toulouse, Toulouse, France

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). During pregnancy, oxidative stress and eNOS dysfunction are the causes of poor placentation due to the decreased NO bioavailability which affects cytotrophoblast migration, spiral artery remodelling and the maintenance of blood flow ( Osol et al. 2017

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DOI:
https://doi.org/10.1530/REM-22-0013
Volume/Issue:
Volume 2022: Issue 1
Open access
Salvatore Sutti Department of Health Sciences and Interdisciplinary Research Centre for Autoimmune Diseases, University of East Piedmont, Novara, Italy

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Emanuele Albano Department of Health Sciences and Interdisciplinary Research Centre for Autoimmune Diseases, University of East Piedmont, Novara, Italy

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). This indicates that the presence of liver inflammation not only is the driving force for the disease evolution to cirrhosis and HCC but might also specifically contribute to extrahepatic injury. Oxidative stress in NAFLD/NASH The involvement of

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Review Article
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Alteration of redox homeostasis and liver diseases
DOI:
https://doi.org/10.1530/REM-22-0002
Volume/Issue:
Volume 2022: Issue 1
Open access
Cristina Russo Section of Pathology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy

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Maria Stella Valle Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy

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Lucia Malaguarnera Section of Pathology, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy

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. 2018 , Valle et al. 2021 a , Russo et al. 2022 ). Therefore, all pathological conditions characterized by systemic inflammation and oxidative stress can impair muscle functionality by triggering enzymatic alterations and mitochondrial

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Effects of anti-aging redox medicine
DOI:
https://doi.org/10.1530/REM-23-0013
Volume/Issue:
Volume 2023: Issue 1
Open access
Cristina Mas-Bargues Freshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable-Instituto de Salud Carlos III (CIBERFES-ISCIII), INCLIVA, Valencia, Spain

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Consuelo Borrás Freshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable-Instituto de Salud Carlos III (CIBERFES-ISCIII), INCLIVA, Valencia, Spain

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José Viña Freshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable-Instituto de Salud Carlos III (CIBERFES-ISCIII), INCLIVA, Valencia, Spain

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Oxidative stress-related mechanisms in HIV infection and treatment A brief introduction to HIV and oxidative stress Human immunodeficiency virus (HIV) is a virus that attaches to the CD4 molecules and CCR5 (a chemokine co-receptor); then

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Review Article
DOI:
https://doi.org/10.1530/REM-22-0017
Volume/Issue:
Volume 2022: Issue 1
Open access
Jacques Kaminski Université de Bourgogne, laboratoire Bio-PeroxIL / INSERM 6 Boulevard Gabriel, Dijon, France

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Marc Haumont Laboratoire Lara-Spiral, 3 rue des Mardors, Couternon, France

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Emmanuelle Prost-Camus Laboratoire Lara-Spiral, 3 rue des Mardors, Couternon, France

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Philippe Durand Laboratoire Lara-Spiral, 3 rue des Mardors, Couternon, France

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Michel Prost Laboratoire Lara-Spiral, 3 rue des Mardors, Couternon, France

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Gérard Lizard Université de Bourgogne, laboratoire Bio-PeroxIL / INSERM 6 Boulevard Gabriel, Dijon, France

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Norbert Latruffe Université de Bourgogne, laboratoire Bio-PeroxIL / INSERM 6 Boulevard Gabriel, Dijon, France

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in the elderly over 65 years old, is associated with important oxidative stress and with inflammation which are supposed to play key roles in its pathophysiology ( Hammami et al. 2020 , Chen et al. 2022 , Pothier et al. 2022 ). Identifying

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DOI:
https://doi.org/10.1530/REM-23-0002
Volume/Issue:
Volume 2023: Issue 1
Open access
Carlo Cervellati Department of Translational Medicine and for Romagna, University of Ferrara, Via Luigi Borsari, Ferrara, Italy

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Paolo Casolari Interdepartmmental Study Center for Inflammatory and Smoke-Related Airway Diseases, Cardiorespiratory and Internal Medicine Section, University of Ferrara, Ferrara, Italy

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Alessandra Pecorelli Department of Environmental and Prevention Sciences, University of Ferrara, Via Luigi Borsari, Ferrara, Italy

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Claudia Sticozzi Department of Life Sciences, University of Siena, Via Aldo Moro, Siena, Italy

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Francesco Nucera Pneumologia, Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali (BIOMORF), Università di Messina, Messina, Italy

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Alberto Papi Interdepartmmental Study Center for Inflammatory and Smoke-Related Airway Diseases, Cardiorespiratory and Internal Medicine Section, University of Ferrara, Ferrara, Italy

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Gaetano Caramori Pneumologia, Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali (BIOMORF), Università di Messina, Messina, Italy

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Giuseppe Valacchi Department of Environmental and Prevention Sciences, University of Ferrara, Via Luigi Borsari, Ferrara, Italy
Department of Animal Science, Plants for Human Health Institute, North Carolina State University, Kannapolis, North Carolina, USA
Department of Food and Nutrition, Kyung Hee University, Seoul, Korea

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mechanism underlying COPD. Oxidative stress has been also shown to play a primary role in COPD onset and clinical progression ( Nucera et al. 2022 ). This chronic inflammation of the lower airways is characterized by a progressive loss of lung parenchyma

Article Type:
Research Article
DOI:
https://doi.org/10.1530/REM-23-0012
Volume/Issue:
Volume 2023: Issue 1
Open access