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phospholipids and carotenoids in the macula ( Johra et al. 2020 ), thus reducing the oxidative stress burden in the eye. Due to the AREDS study design and the fact that vitamin E was part of the initial beneficial nutrient cocktail and therefore considered
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monolayers, confirmed the oxysterol mixture action in inducing oxidative stress and inflammatory cytokine production in differentiated cells primarily involving NOX1, JNK1/2-p38 MAPK and NF-κB signaling axis ( Guina et al. 2015 , Serra et al. 2018
Department of Translational Medicine, University of East Piedmont, Novara, Italy
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of histone H3 at lysine 27 by activating oxidative stress; effect of nutrient interventions . Free Radical Biology and Medicine 210 462 – 477 . ( https://doi.org/10.1016/j.freeradbiomed.2023.11.043 ). Leoni V Nury T Vejux A Zarrouk A Caccia
