Effects of Anti-aging Redox Medicine on Health and Lifespan


Effects of anti-aging Redox medicine on health and lifespan special collection banner


This special collection is led by Editor-in-Chief Professor Giuseppe Poli, alongside Guest Editors Enrique Cadenas and Ettore Bologna.

The collection will include review articles contributed by presenters of the 2023 Oxygen Club of California (OCC) Workshop, which forms part of Healthy Aging Week 2023.

Anti-aging redox medicine aims to mitigate cell and tissue damage induced by oxidants (oxidative stress), to maintain or restore optimal mitochondrial function, to promote a balanced immune response and reduce but also prevent chronic inflammatory processes, the latter being well known promoters of cardiovascular, neurodegenerative, metabolic and neoplastic diseases. Certain pathways and genes, such as those associated with sirtuins and mTOR (mammalian target of rapamycin), are implicated in the regulation of longevity and aging. Redox signalling molecules are known to interact with these pathways, and targeting these interactions through redox medicine should contribute to promote healthier aging and well-being. It may also contribute to extended lifespan. Last but not least, by preserving the function of tissues and organs and reducing the burden of age-related damage, redox medicine could potentially increase the number of healthy, disease-free years in an individual's life (personalized medicine).

The editors welcome submissions of original research for inclusion in this collection. Please submit to the journal stating in your cover letter that you wish for your article to be considered for this special collection. Alternatively please email the editorial office rem@bioscientifica.com for further information.


Read the latest articles published in the special series:


Metformin and its redox-related mechanisms of action in type 2 diabetes
Teresa Vezza, Clara Luna-Marco, Susana Rovira-Llopis and Victor M Victor

Antioxidative effects of vitamin D in muscle dysfunction
Cristina Russo, Maria Stella Valle and Lucia Malaguarnera

Selected phenolic compounds in the modulation of biochemical pathways in ageing
Ludovica Spagnuolo, Diana Lelli, Greta Lattanzi, Laura Dugo, Claudio Pedone and Laura De Gara

Current evidence of the role of vitamin E in prolonging a healthy life
Maret Traber

Carotenoid Basics: From Food to Skin
Daniela Weber and Tilman Grune

Redox control of signalling responses to contractile activity and aging in skeletal muscle
Malcolm J Jackson

Intake of palmitic acid and its association with metabolic flexibility in middle-aged individuals: a preliminary study
Elisabetta Murru, Gianfranca Carta, Claudia Manca, Alessia Leone, Chiara Murru, Michele Ruggiu, Roberto Solinas, Roberta Montisci, Filippo Tocco and Sebastiano Banni

Involvement of mTOR signaling in physiopathology and its potential therapeutic interventions
Irene Martín-Bocanegra, Thaissa Horne, Belén Maqueda-Hernández, Elena Navarro-Villarán, and Jordi Muntané